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Korean Journal of Neuromuscular Disorders 2015;7(1):45-47.
Steroid Responsive Encephalopathy in Patient with MELAS Syndrome
Byoung-Jun Yun, Min-Oh Lee, Soo-Hyun Park, Nam-Hee Kim
Department of Neurology, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea
MELAS 증후군 환자에서 스테로이드에 반응을 보인 뇌병증
윤병준, 이민오, 박수현, 김남희
동국대학교 의과대학 일산병원 신경과
Abstract
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is a common mitochondrial disease that can cause a wide range of clinical symptoms. We describe a 26-year-old woman diagnosed with MELAS presenting recurrent episodes of seizures, right sided weakness, visual field defect, and cognitive decline. These recurrent symptoms improved after high dose corticosteroid treatment, and three months’ maintenance of steroid prevented further recurrence of encephalopathy. Corticosteroid therapy may be beneficial during acute exacerbation of MELAS.
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