Current Concept of Guillain-Barré Syndrome.

Lee, Seon Ah; Kim, Jee Eun

Review article

Korean Journal of Neuromuscular Disorders 2019;11(1):18-26.
Published online July 22, 2019.

Current Concept of Guillain-Barré Syndrome.

¹Research Institute, Seoul Medical Center, Seoul, Korea.
²Department of Neurology, Seoul Medical Center, Seoul, Korea. junenr@gmail.com

Abstract

Guillain-Barré syndrome (GBS) is nowadays consider as an umbrella term that has heterogenous presentation depend on their subtypes. GBS is clinical diagnosis and its diagnosis can be supported by laboratory findings from cerebral spinal fluid study, nerve conduction study, anti-ganglioside antibodies, spinal magnetic resonance imaging and nerve ultrasound. Understanding atypical subtypes and GBS mimicking diseases are crucial for correct diagnosis. Both proper medical care for respiratory and autonomic dysfunction and immunotherapy are essential to improve outcome of GBS. Here, we summarized the current concept on diagnosis, immunopathophysiology and treatment of GBS.

Key Words: Guillain-Barré syndrome, Diagnosis, Treatment