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Korean Journal of Neuromuscular Disorders 2018;10(2):17-21.
Autonomic Dysfunctions in Multiple System Atrophy
Jae Jung Lee, Joong-Yang Cho
Department of Neurology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea
다계통 위축증의 자율신경 장애
이재정, 조중양
인제대학교 의과대학 일산백병원 신경과
Abstract
Multiple system atrophy is a disabling neurodegenerative disorder that is characterized by autonomic dysfunctions associated with abnormal movement phenomena, such as Parkinsonism or cerebellar ataxia. An autonomic dysfunction is a feature of synucleinopathies associated with Parkinson’s disease, Dementia with Lewy bodies, and pure autonomic failure, hence differential diagnosis of multiple system atrophy is often challenging. In this study, dysautonomic manifestations frequently observed in multiple system atrophy, and their anatomical correlates with pathophysiology are described.
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