| A Case of Acute Neuropathy Associated with Low Thiamine Level Following Treatment with Arsenic Trioxide for a Patient with Acute Promyelocytic Leukemia |
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Jee Eun Yoon, Jun-Sang Sunwoo, Ji Sun Kim, Kyung Bok Lee, Moo-young Ahn, Hakjae Roh |
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| 급성전골수세포백혈병 환자에게 비소요법 시행 후 발생한 티아민 저하와 연관된 급성 신경병증 |
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윤지은, 선우준상, 김지선, 이경복, 안무영, 노학재 |
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| Abstract |
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Arsenic trioxide has been steadily used as a treatment for acute promyelocytic leukemia over the decade. Peripheral neuropathy is a common complication of arsenic therapy and the symptoms are usually mild and reversible following discontinuation of the therapy. However, the clinical course of arsenic neurotoxicity in patient with coexistence of thiamin deficiency may potentially lead to be severe weakness and bad prognosis. It is important to determine the serum thiamine level of patients with acute promyelocytic leukemia before administrating Arsenic trioxide |
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