Electrophysiological and Laboratory Diagnosis of Myopathy

Shin, Je-Young; Sung, Jung-Joon

Review article

Korean Journal of Neuromuscular Disorders 2016;8(1):10-21.

Je-Young Shin, Jung-Joon Sung

Department of Neurology, Seoul National University Hospital, Seoul, Korea

전기생리검사 및 검사실 검사를 이용한 근육병의 진단

신제영, 성정준

서울대학교병원 신경과

Abstract

Myopathies are a heterogeneous group of disorders that can be challenging to diagnose. There are several diagnostic tests for the evaluation of patients with myopathy. Creatine kinase (CK), electromyography can be used to confirm myopathy. Ancillary tests such as ischemic forearm exercise tests, autoantibody tests, muscle magnetic resonance imaging should be considered in certain patients. Muscle biopsy is a crucial test in differential diagnosis of myopathies. Recent advances in genetic analysis have led to more fast and convenient diagnosis of myopathy. The appropriate application of these various diagnostic studies will bring accurate diagnosis to the patients with myopathy.