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Korean Journal of Neuromuscular Disorders 2014;6(2):54-56.
Isolated Bilateral Abducens Nerve Palsies with Anti?GQ1b Antibodies
Hak-Ju Oh, Suk Yun Kang, Sun-Young Im, Soo-Jin Cho, Joo Yong Kim, Ki-Han Kwon
aDepartment of Neurology, Chuncheon Sacred Hospital, Hallym UniversityHallym University College of Medicine, Chuncheon; bDepartment of Neurology, Dongtan Sacred Hospital, Hallym University College of Medicine, Hwaseong; cDepartment of Neurology, Pyeongchon Sacred Hospital, Hallym University College of Medicine, Anyang, Korea
항 GQ1b 항체와 연관된 단독 양측외전신경마비
오학주, 강석윤, 임선영, 조수진, 김주용, 권기한
한림대학교 의과대학 춘천성심병원 신경과학교실a, 한림대학교 의과대학 동탄성심병원 신경과학교실b, 한림대학교 의과대학 평촌성심병원 신경과학교실c
Abstract
Bilateral abducens nerve palsies is mainly caused by cancer, vascular diseases, demyelinating disease like Guillian-Barre’s syndrome (GBS), myasthenia gravis and infection. The diseases which increasing intracranial pressure may also result in bilateral abducens nerve palsies. Isolated bilateral abducens nerve palsies is very rare. Here, we report a 24-year-old man who presented isolated bilateral abducens nerve palsies with anti GQ1b antibodies. He did not have any other neurologic deficit including ataxia and loss of deep tendon reflexes. This is the meaningful report of a patient with isolated bilateral abducens nerve palsies associated with anti-GQ1b antibodies. This case suggests that anti-GQ1b antibody syndrome should be considered when we meet a patient with unexplained isolated bilateral abducens nerve palsies.
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