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Korean Journal of Neuromuscular Disorders 2010;2(1):21-25.
Inclusion Body Myositis
Gyoungim Suh, Ji-Man Hong, Young-Chul Choi
Department of Neurology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea
봉입체근육염
서경임, 홍지만, 최영철
연세대학교 의과대학 신경과학교실
Abstract
Inclusion body myositis (IBM) is the most common idiopathic inflammatory myositis in patients over the age of 50 years. Prevalence of IBM varies among countries and ethnic groups. Etiology and pathogenesis of IBM is still unknown. It may be primary degenerative myopathy or autoimmune inflammatory myopathy or both. Asymmetrical weakness of the quadriceps and flexor forearm muscles are the clinical key of IBM. This review covers clinical presentation, pathogenesis, diagnosis and treatment of IBM.
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