| A Guillain-Barré Syndrome with Anti-GQ1b and Anti-GT1a Antibodies Positivity Manifesting with Acute Bulbar Palsy and Subsequent Delayed Ophthalmoplegia |
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Seonmin Yoon1, Jong Seo Bae1, Byeol-A Yoon2, Jong Kuk Kim2, Yerim Kim1, Sang-Hwa Lee3 |
1Department of Neurology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea
2Department of Neurology, Dong-A University Hospital, Busan, Korea
3Department of Neurology, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea |
| 연수마비로 시작하여 지연성 안근마비가 순차적으로 발생한 항GQ1b와 항GT1a 양성 길랭-바레 증후군 |
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윤선민1, 배종석1, 윤별아2, 김종국2, 김예림1, 이상화3 |
1한림대학교 의과대학 강동성심병원 신경과
2동아대학교병원 신경과
3한림대학교 의과대학 춘천성심병원 신경과 |
Correspondence:
Sang-Hwa Lee, Tel: +82-33-240-5255, Fax: +82-33-241-8063,
Email: bleulsh@naver.com
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Received: 4 February 2020 • Revised: 9 April 2020 • Accepted: 23 December 2020 |
| Abstract |
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In Guillain-Barré syndrome (GBS) and its variant, anti-GQ1b antibody has a pathogenic role for ophthalmoplegia. In addition, anti-GT1a antibody is related with lower cranial nerve involvement. This report describes a 60-year-old male patient with GBS manifesting with initially isolated dysphagia and subsequently developed ophthalmoplegia. Both immunoglobulin G type anti-GQ1b and anti-GT1a antibodies were detected in the patient’s serum. A mechanism regarding subsequent involvement of respective cranial nerves remains to be elucidated. |
| Key Words:
Gangliosides, Bulbar palsy, Ophthalmoplegia |
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