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Korean Journal of Neuromuscular Disorders 2018;10(2):41-44.
Lewis-Sumner Syndrome; Extensive Cranial and Cervical Root Involvement on MR Imaging
Sun-Young Kim, Ha Young Shin
1Department of Neurology, Ulsan University Hospital, Ulsan University College of Medicine, Ulsan; 2Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
MR 영상에서 뇌신경 및 경추 뿌리 신경을 광범위하게 침범한 루이스 솜너 증후군 1예
김선영, 신하영
울산대학교 의과대학 울산대학교병원 신경과1, 연세대학교 의과대학 신경과학교실2
Abstract
A 33-year-old woman, previously diagnosed with multifocal acquired demyelinating sensory and motor neuropathy, or Lewis-Sumner syndrome (LSS), presented with diffuse multifocal nerve root swelling at cervical 3th to 7th resembling with neurofibroma. Upon nerve conduction investigations, multifocal conduction block in the upper limb were discovered. In addition, a right mandibular branch of trigeminal nerve hypertrophy resembling schwannoma was found Treatment with intravenous immunoglobulin and steroid improved her symptoms. The observed hypertrophy in the right mandibular branch of the trigeminal nerve was correlated with her symptoms. This study presents a case of LSS mimicking neurofibroma with coexisting cranial and peripheral nerve involvement, emphasizing the usefulness of the magnetic resonance imaging.
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